Christina Applegate arrives at the 15th Annual Screen Actors Guild Awards held at the Shrine Auditorium on January 25, 2009 in Los Angeles, California.Michael Buckner/WireImage.com - Monday, January, 26, 2009, 10:26 PM

Christina Applegate stars as Samantha in Samantha Who? ABC/Bob D'Amico - Friday, October, 31, 2008, 10:31 PM

Christina Applegate arrives to the 2007 American Music Awards.Steve Granitz/WireImage.com - Friday, December, 14, 2007, 9:14 PM

Christina Applegate arrives at the ABC Summer Press Tour Party.Jesse Grant/WireImage.com - Monday, October, 22, 2007, 10:22 PM

Christina Applegate at the 61st Annual Tony Awards.Jim Spellman/WireImage.com - Monday, October, 22, 2007, 10:22 PM

Christina Applegate at the "A Fine Romance" Gala Benefiting the Motion Picture & Television Fund.Jeffrey Mayer/WireImage.com - Monday, October, 22, 2007, 10:22 PM

Christina Applegate stars as Samantha in Samantha Who? ABC/Craig Sjodin - Monday, July, 30, 2007, 11:30 PM

Christina Applegate at The 55th Annual Primetime Emmy Awards.Jeffrey Mayer/WireImage.com - Friday, July, 6, 2007, 12:6 AM

Christina Applegate at The 55th Annual Primetime Emmy Awards.George Pimentel/WireImage.com - Friday, July, 6, 2007, 12:6 AM

Christina Applegate at The 33rd Annual People's Choice Awards. Gregg DeGuire/WireImage.com - Wednesday, January, 10, 2007, 8:10 PM

Premiere: Christina Applegate at the Disneyland premiere of Walt Disney Pictures' Pirates of the Caribbean: Dead Man's Chest - 6/24/2006Steve Granitz, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate at the Disneyland premiere of Walt Disney Pictures' Pirates of the Caribbean: Dead Man's Chest - 6/24/2006Steve Granitz, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate and Will Ferrell at the Hollywood premiere of Dreamworks' Anchorman - 6/28/2004Steve Granitz, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate and Will Ferrell at the Hollywood premiere of Dreamworks' Anchorman - 6/28/2004Albert L. Ortega, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate and Johnathon Schaech at the New York premiere of Dreamworks' Anchorman - 7/7/2004Jim Spellman, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate and Johnathon Schaech at the New York premiere of Dreamworks' Anchorman - 7/7/2004Dimitrios Kambouris, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Will Ferrell and Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Jim Spellman, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Will Ferrell and Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Jim Spellman, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Will Ferrell and Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Jim Spellman, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Will Ferrell and Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Dimitrios Kambouris, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Dimitrios Kambouris, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Dimitrios Kambouris, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Dimitrios Kambouris, WireImage.com - Thursday, September, 21, 2006, 11:21 PM

Premiere: Christina Applegate at the New York premiere of Dreamworks' Anchorman - 7/7/2004Jim Spellman, WireImage.com - Thursday, September, 21, 2006, 11:21 PM